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Actinobacillus pleuropneumoniae (APP)
- Respiratory distress is severe; there is thumping and occasionally open-mouth breathing with a blood-stained frothy nasal and oral discharge, fever, anorexia, and reluctance to move.
Diagnosis
- An explosive disease onset is suggestive.
- The pneumonia is usually bilateral.
- The characteristic lesion is a severe fibrinonecrotic and hemorrhagic pneumonia with accompanying fibrinous pleuritis.
- In acute cases, the lungs are dark and swollen and ooze bloody fluid from the cut surface.
- Hemorrhagic, even necrotic bullae (cavities) of various sizes may be present.
- The trachea may contain blood-stained froth. Bloody nasal/oral discharge is common.
- In chronic cases, the lesions are more organized and localized.



