Swine Influenza Virus
- Respiratory: coughing, rapid breathing (thumping), depression, fever to 108°F, anorexia, dyspnea, weakness, prostration and a mucous discharge from the eyes and nose.
- Outbreak is characterized by sudden onset and rapid spread through the entire herd, often within 1-3 days.
SIV Strain Variation and the Consequences for Vaccination Programs: The Importance of Diagnostic Monitoring
Genetic sequencing of SIV is an effective tool in evaluating changes in the virus. Even more importantly, analysis of the amino acid variation at the crucial antigenic sites (epitopes) can be used to determine significant (antigenically relevant) differences.
A Unique High Throughput Serum Neutralization Assay to Categorize Swine Influenza Virus Isolates
Over the past decade, swine influenza virus (SIV) isolates have exhibited significant genetic and antigenic diversity. Traditionally, disease surveillance programs and vaccine candidate selection techniques have relied on partial HA gene sequencing to subtype and genetically characterize influenza isolates.